The Netherlands

UMC Utrecht

ALS Centre Netherlands is the national centre of expertise on ALS, PLS and PMA in the Netherlands. The centre is a cooperation of the University Medical Centre Utrecht and the Amsterdam Medical Centre. The centre schedules all diagnostic research and consultations for each patient on one day. A large majority of around 90% of all Dutch ALS patients are diagnosed at ALS Centre Netherlands. In total, more than 500 patients are diagnosed with ALS, PLS, PMA or one of its mimics each year. Prof. Leonard van den Berg, director of the ALS Centre Netherlands is one of the initiators of the TRICALS platform with the aim to speed up the research for a treatment for ALS by increased collaboration between patients, the industry and ALS centres. He is also one of the initiators of Project Mine (www.projectmine.com), the largest research of the genetic basis of ALS worldwide. Additionally, the research focuses on epidemiology, brain imaging and cognitive functioning of ALS patients.

Details

Foundation year

1998

Director

Prof. dr. Leonard H. van den Berg

Principal investigator(s)

Prof. dr. Leonard H. van den Berg
Prof. dr. Jan Veldink
Prof. Jeroen Pasterkamp

Neurologists

Prof. dr. Leonard van den Berg
Prof. dr. Jan Veldink
Dr. Michael van Es
Dr. Stephan Goedee

Research nurses

Tommy Bunte
Andrea van Zijl
Arianne de Jong-de Fockert

Motto

“All patients deserve a chance to participate in a clinical trial.”

Team

Clinical trials

Type Name no patients
Industry sponsored

Masitinib trial ABscience (AB10015)

10

CHDR1417 – phase 1 trial

18

Levals (ODM-109)

5

TW001 Treeway

10

Vitality-ALS Cytokinetics

10

VEGF trial NEWRON Sweden (sNN0029)

5

Ozanezumab 2014 (GSK1223249)

22

Tirasemtiv Benefit Trial 2013 (CK-2017357)

12

Envision 2012 (KNS-760704)

28

EMPOWER 2011 (KNS-760704)

28

Alstar 2009

13

ONO 2007

26

Investigator initiated

LITRA 2008 (Lithium)

130

Natriumvalproaat 2005

188

Ongoing observational studies

Prospective ALS Study Netherlands (PAN)  2479

Publications

Have a look at our most recent publications.

Contact information

ALS Centre Netherlands, UMC Utrecht

Heidelberglaan 100, 3584 XC, Utrecht Netherlands
Contact: Akke Albada (communications officer)
+31 88 755 7939
info@als-centrum.nl
research.umcutrechthersencentrum.nl/neuromuscular-disorders/