Hôpital de la Salpêtrière

To understand the disease mechanisms at work in ALS, our first objective was to perform clinical research and study the natural disease course of ALS. This strategy led to the first successful clinical trial in 1994. Beside our current involvement with clinical trials, we acquired an expertise in muscle biomarkers, genetics and neuroimaging.

Contact
Location
Hôpital de la Salpêtrière, Boulevard de l'Hopital, Paris, France

Specialists

François Salachas

Coordinator and Investigator of research

Dr. François Salachas is Coordinator and Investigator of research in Hôpital Pitié-Salpêtrière.

François Salachas
Current trials
Recruiting
Phase iii

ALXN1210-ALS-308 trial

Industry trial
This phase 3 trial aims to study the safety and efficacy of the drug ‘ravulizumab’ in people living with ALS. To register for this study, you should contact your local ALS centre or treating physician.
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Recruiting
Phase iii

VALOR study

Industry trial
Biogen is conducting a clinical trial to evaluate the safety and potential efficacy of an investigational drug for people with Amyotrophic Lateral Sclerosis (ALS) with a SOD1 gene mutation.
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In preparation
Phase iii

The Lighthouse 2 trial

Investigator initiated trial
The Lighthouse 2 study is a phase 3 clinical trial in which we will investigate the efficacy of the drug Triumeq.
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In preparation
Phase iii

MAGNET

Platform trial
MAGNET is an innovative clinical platform trial in which multiple treatments for ALS are investigated simultaneously.
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Recruiting
Phase iii

TUDCA-ALS

Investigator initiated trial
This trial will evaluate the efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment for people with ALS.
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