We schedule all diagnostic research and consultations for each patient on one day. Around 90% of all Dutch ALS patients are diagnosed in our centre and over 500 patients are diagnosed each year. Prof. Leonard van den Berg, director of the ALS Centre Netherlands, is one of the initiators of the TRICALS platform with the aim to speed up the research for an ALS treatment by increasing collaboration between patients, industry and ALS centres. He is also one of the initiators of Project Mine (www.projectmine.com), which is the largest research effort worldwide to study the genetic basis of ALS. Additionally, our research focuses on epidemiology, brain imaging and cognitive functioning of ALS patients.