ALS Centre Netherlands

UMC Utrecht

ALS Centre Netherlands is the national centre of expertise on ALS, PLS and PMA in the Netherlands.

Logo-UMC-Utrecht-2019_4
UMC Utrecht

ALS Centre Netherlands schedules all diagnostic research and consultations for each patient on one day. A large majority of around 90% of all Dutch ALS patients are diagnosed at ALS Centre Netherlands. In total, more than 500 patients are diagnosed with ALS, PLS, PMA or one of its mimics each year. Prof. Leonard van den Berg, director of the ALS Centre Netherlands is one of the initiators of the TRICALS platform with the aim to speed up the research for a treatment for ALS by increased collaboration between patients, the industry and ALS centres. He is also one of the initiators of Project Mine (www.projectmine.com), the largest research of the genetic basis of ALS worldwide. Additionally, the research focuses on epidemiology, brain imaging and cognitive functioning of ALS patients.

Contact
Location
Heidelberglaan 100, 3584 CX Utrecht, Nederland

Specialists

Leonard van den Berg

Professor of Neurology

Professor Leonard van den Berg is professor of Neurology and coordinator of the ALS Centre Netherlands.

Leonard van den Berg
Current trials
In preparation
Phase iii

PreLude (Lithium carbonate)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of lithium carbonate in UNC13a homozygous patients.

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In preparation
Phase ii

Lighthouse (Triumeq)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of Triumeq, a therapy developed for treatment of HIV that has shown to slow progression in ALS

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In preparation
Phase iii

iAdore (Oral edaravone)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of oral edaravone (TW001), a formulation that reduces oxidative stress

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