Prof McDermott studied for his medical degree at the University in Leeds. He then continued his medical and specialist neurology training in Leeds followed by a clinical research training fellowship at the University of Newcastle upon Tyne. He moved to the University of Sheffield for his doctoral studies and to complete his Specialist Training in Neurology to become a Consultant Neurologist. Prof McDermott is now the Professor of Translational Neurology at SITraN and a Consultant Neurologist at the Sheffield Teaching Hospitals Foundation NHS Trust regularly undertaking specialist MND and neuromuscular clinics in Sheffield. The main drive of Prof McDermott’s research programme is developing the evidence base for delivering supportive and symptomatic care for patients living with motor neuron disease. He is chair of the NIHR UK MND Clinical Studies Group and is experienced in ALS clinical trials.