I have had experience in neuromuscular disorders both from a clinical and basic science point of view since the first years of Medical School. For the past 22 years I have been looking after in-patients with muscle disorders at the University Department of Neurology in Milan and I have also been in charge of the State-run out-patient neuromuscular clinic at the Hospital Site. My main field of research has been myotonic disorders, especially the myotonic dystrophies. Since 2010 I have worked as a CINCH co-PI (International Consortium of Inherited Channelopathies), recruiting participants for clinical studies. These clinical studies have given me experience in conducting clinical trials, in overcoming obstacles in patient recruitment and retention, in addressing challenges of drug supply, pursuing US, Italian and local regulatory approvals and working productively with clinical study groups. Since I became Clinical Director of the NEMO Center in 2013, I have extended my field of research in other muscular dystrophies, including ALS. Since 2019 I am the Scientific Director of the Nemo Clinical Research Center at the NEMO Center in Milan, a dedicated university neurorehabilitation unit for neuromuscular patients and I am Professor of Neurology at the university of Milan since 2006.