Trials

6 trials
Recruiting

A phase 1, double-blind, randomized, placebo-controlled, multi-center, single- and multiple-ascending-dose study to determine initital safety, tolerability, and pharmacokinetics of GDC-0134 in patients with Amyotrophic Lateral...

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Active

Observational methodology study of novel electrophysiological, physical, and imaging outcome measures to assess the progression of ALS. The primary objectives of the study are to...

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Completed

Understanding clinical phenotype and collecting biomarker samples in C9ORF72 ALS This research study is being performed to better understand a specific form of ALS caused...

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Completed

A prospective, multicenter, randomized, double-blind, placebocontrolled, parallel groups, phase 2/3 study to compare the efficacy and safety of masitinib versus placebo in the treatment of...

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Completed

A phase I, randomized, double blind, double-dummy placebo controlled, 3-way cross-over study to determine the test-retest reliability of, and the effect of oral retigabine and...

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Completed

A Phase 3, multi-national, double-blind, randomized, placebo-controlled, stratified, parallel group, study to evaluate the safety, tolerability and efficacy of Tirasemtiv in patients with Amyotrophic Lateral...

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