Karolinska Institute

The Karolinska ALS Clinical Research Group was created by Caroline Ingre in 2015. In 2018, thanks to a fundraising organized by Sebastian and Kristin Penner from Stoppa ALS, the Clinical Trial part was funded, making ALS trials more accessible in Sweden. Since then, our group has become the most active ALS trial center in the Nordic countries. The Karolinska ALS Clinical Research Group also conducts pre-clinical and clinical research focusing on ALS biomarkers, genetics, neuro-immunology, neuroimaging, cardiac involvement, diagnostic delay factors, cognition and behavioral impairment, risks factors, access to trials and more. We also started the National ALS/MND Quality Registry, collecting data on all ALS/MND patients in Sweden. Our activities are divided between the Karolinska University Hospital, the Karolinska Institutet, and the S-ASC unit (Studieenheten Akademiskt Specialistcentrum) where we run our ALS trials.