ALS trial research

The highway towards a cure

TRICALS is the largest European research initiative to find a cure for ALS to date. 40 top research centres in 14 countries have joined hands with patient organisations and fundraisers to reach our one goal: find effective treatments for ALS.

Find out more about the highway 
towards a cure in this video.
Creating a world without ALS, together

The very best experts from top research centres around the globe have teamed up with patient organisations, fundraisers and pharma companies in a unique international collaboration to find a cure for ALS

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The best research centers

Top research centres in 14 countries have joined hands with patients’ organisations and fundraisers to reach our one goal: find a treatment for ALS within 5 years

Make a difference

Join us in our mission to make ALS treatable. Support one of our running campaigns or start your own. Together we will create a world without ALS.

Become a fundraiser

Danny - patient

The perfect platform to unite

“I believe TRICALS will be the perfect platform to unite patients, pharma and researchers that want to contribute to get rid of this disease”

Current trials
Recruiting
Phase iii

ALXN1210-ALS-308 trial

Industry trial
This phase 3 trial aims to study the safety and efficacy of the drug ‘ravulizumab’ in people living with ALS. To register for this study, you should contact your local ALS centre or treating physician.
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Recruiting
Phase iii

VALOR study

Industry trial
Biogen is conducting a clinical trial to evaluate the safety and potential efficacy of an investigational drug for people with Amyotrophic Lateral Sclerosis (ALS) with a SOD1 gene mutation.
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In preparation
Phase iii

The Lighthouse 2 trial

Investigator initiated trial
The Lighthouse 2 study is a phase 3 clinical trial in which we will investigate the efficacy of the drug Triumeq.
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In preparation
Phase iii

MAGNET

Platform trial
MAGNET is an innovative clinical platform trial in which multiple treatments for ALS are investigated simultaneously.
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Recruiting
Phase iii

TUDCA-ALS

Investigator initiated trial
This trial will evaluate the efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment for people with ALS.
Read more

News & Events

Latest news

Webinar recording "Efficient Patient Identification in ALS Clinical Trials" now available
Webinar recording "Efficient Patient Identification in ALS Clinical Trials" now available
Two weeks ago, we presented the free webinar: “Efficient Patient Identification in…
The ALXN1210 trial is recruiting participants
The ALXN1210 trial is recruiting participants
This phase 3 trial, which is sponsored by Alexion Pharmaceuticals, aims to…
Free Webinar: Efficient Patient Identification in ALS Clinical Trials
Free Webinar: Efficient Patient Identification in ALS Clinical Trials
In collaboration with Julius Clinical, TRICALS will present the webinar: “Efficient Patient…
The VALOR Study – A Clinical Trial for People Living with SOD1-ALS
The VALOR Study – A Clinical Trial for People Living with SOD1-ALS
Biogen is conducting a clinical trial to evaluate the safety and potential…
Do you have any questions?

For general inquiries please contact us by using the contact form. For questions about clinical trials, please contact a TRICALS center close to you.