ALS trial research

The highway towards a cure

TRICALS is the largest European research initiative to find a cure for ALS to date. 42 top research centers in 16 countries have joined hands with patients’ organisations and fundraisers to reach our one goal: find a treatment for ALS within 5 years.

Find out more about the highway 
towards a cure in this video.
Creating a world without ALS, together

The very best experts from top research centres around the globe have teamed up with patients’ organisations, fundraisers and pharma companies in a unique international collaboration to find a cure for ALS

Top experts from 16 countries

Top experts from 16 countries
The best research centers across Europe

Top research centers in 16 countries have joined hands with patients’ organisations and fundraisers to reach our one goal: find a treatment for ALS within 5 years

Danny - patient

The perfect platform to unite

“I believe TRICALS will be the perfect platform to unite patients, pharma and researcher that want to contribute to get rid of this disease”

Current trials
In preparation
Phase iii

PreLude (Lithium carbonate)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of lithium carbonate in UNC13a homozygous patients.

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In preparation
Phase ii

Lighthouse (Triumeq)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of Triumeq, a therapy developed for treatment of HIV that has shown to slow progression in ALS

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In preparation
Phase iii

iAdore (Oral edaravone)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of oral edaravone (TW001), a formulation that reduces oxidative stress

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Do you have any questions?

Contact a TRICALS centre close to you