Orla Hardiman

Orla Hardiman

Professor of Neurology

Professor Hardiman trained in Neurology in Boston prior to her appointment as a Consultant Neurologist at Beaumont Hospital Dublin. In 2011, she established the Academic Unit of Neurology at Trinity College Dublin and was appointed the first Professor of Neurology in the country in 2013. In 2015 she was elected as a Fellow of Trinity College Dublin, and was of the first three active clinicians ever to be elected as a Member of the Royal Irish Academy in 2015. She is the recipient of many international honours and awards, and a recognized world leader in ALS and FTD research. Her research interests are in clinical and translational neuroscience and she is world leader in the epidemiology, phenotype, genomics and neural networking of Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, and related conditions. She has published over 350 peer reviewed publications, and her work is funded by the Health Research Board, Science Foundation Ireland, and the charities ALSA and MNDA, IMNDA and RMN.

Connect
Connect trials
Recruiting
Phase iii

PHOENIX trial

Industry trial

Amylyx Pharmaceuticals Inc is conducting a phase 3 trial to determine the safety and efficacy of their compound ‘AMX0035’ for the treatment of ALS.

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Recruiting
Phase iii

ADORE Trial

Industry trial

Ferrer is conducting a phase 3 trial to evaluate the safety and potential efficacy of an investigational drug for people with Amyotrophic Lateral Sclerosis (ALS).

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Recruiting
Phase iii

COURAGE-ALS Trial

Industry trial

In the COURAGE-ALS study, we are investigating the efficacy and safety of the drug ‘reldesemtiv’ for the treatment of ALS. This clinical trial is sponsored by Cytokinetics.

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Active
Phase ii

APL2-ALS-206 Trial

Industry trial

In this phase 2 study, we are investigating the safety and efficacy of the drug pegcetacoplan for the treatment of ALS. This trial is sponsored by Apellis Pharmaceuticals.

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Active
Phase ii

RT001 in Amyotrophic Lateral Sclerosis

Industry trial

In this phase 2 trial, we will study the safety and efficacy of the compound RT001 in people living with ALS. This clinical trial is sponsored by Retrotope Inc.

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Recruiting
Phase iii

TUDCA-ALS

Investigator initiated trial

This trial will evaluate the efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment for people with ALS.

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