Professor Bede is a consultant neurologist specialised in neuromuscular disorders and neurodegenerative conditions. He is the head of the Computational Neuroimaging Group in Trinity College Dublin. His research work focuses on the characterisation of phenotype-specific imaging signatures, genotype-associated brain changes and propagation patterns in vivo, using advanced computational neuroimaging techniques. He has published over 100 peer-reviewed research papers and book chapters on ALS, Primary Lateral Sclerosis, Neuroimaging Methods, MRI Physics, Biostatistics and Frontotemporal Degeneration. He is the associate editor of the ‘Amyotrophic Lateral Sclerosis and Frontotemporal Dementia’ journal and the patron of the Irish Motor Neuron Disease Association (IMNDA). He is a member of the steering committee of the Neuroimaging Society in ALS (NiSALS), the American Academy of Neurology, and the UK MND Association (MNDA) Research Advisory Panel. Professor Bede holds a number of prestigious research grants from national and international funding agencies including the EU-JPND, Health Research Board, RMN and IICN.