ALS Centre, IRCCS Istituto Auxologico Italiano

University of Milan Medical School

The ALS Centre is a referral Institution in Italy for diagnosis and care of patients with ALS and other motor neuron diseases.

Research activities are mainly focused on genetics of ALS, stem cell therapeutics, and functional studies on pathogenetic mechanisms of disease. The ALS Centre is also involved in clinical research aiming at biomarker identication (neuroradiological, neurophysiological, and CSF) and clinical trials.

Contact
Location
International Medical School, University of Milan, Milan, Metropolitan City of Milan, Italy

Specialists

Current trials
Recruiting
Phase iii

TUDCA-ALS (TUDCA)

Industry sponsored trial

TUDCA (tauroursodeoxycholic acid) is a small molecule that is being explored for its potential as a treatment for ALS

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In preparation
Phase iii

PreLude (Lithium carbonate)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of lithium carbonate in UNC13a homozygous patients.

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In preparation
Phase ii

Lighthouse (Triumeq)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of Triumeq, a therapy developed for treatment of HIV that has shown to slow progression in ALS

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In preparation
Phase iii

iAdore (Oral edaravone)

Platform trial arm

Within an innovative platform design study, we will evaluate the efficacy of oral edaravone (TW001), a formulation that reduces oxidative stress

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